MicroRNAs with immune-related functions are associated with differential chromatin marks. A)
Gga-mir-148a and C)
Gga-mir-21 display significantly increased H3K4me3 marks in the resistant line L63 at the latent stage of infection. There are no observed differences between the lines at the cytolytic stage although levels of H3K4me3 appear to be higher. D)
Gga-mir-10b and E)
Gga-mir-137 exhibit increased H3K27me3 marks in line L63 at 10 dpi, while both infected and control L72 birds have high H3K27me3 levels. Both lines show low levels of H3K27me3 at the earlier stage of infection.