Figure 2

MicroRNAs with immune-related functions are associated with differential chromatin marks. A) Gga-mir-155, B) Gga-mir-148a and C) Gga-mir-21 display significantly increased H3K4me3 marks in the resistant line L6₃ at the latent stage of infection. There are no observed differences between the lines at the cytolytic stage although levels of H3K4me3 appear to be higher. D) Gga-mir-10b and E) Gga-mir-137 exhibit increased H3K27me3 marks in line L6₃ at 10 dpi, while both infected and control L7₂ birds have high H3K27me3 levels. Both lines show low levels of H3K27me3 at the earlier stage of infection.