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Table 3 Selected KEGG pathways enriched in MD-induced DMRs

From: Histone modifications induced by MDV infection at early cytolytic and latency phases

Histone DPI Line KEGG pathway Count P-value Adjusted p-value FDR
H3K4me3 5 L72 gga04120:Ubiquitin mediated proteolysis 20 0.011523 0.258461 12.60988
  10 L63 gga03040:Spliceosome 76 1.27E-07 1.83E-05 1.5x10−4
    gga04120:Ubiquitin mediated proteolysis 66 0.070518 0.409344 57.98318
    gga04110:Cell cycle 61 0.071502 0.39873 58.50744
H3K27me3 5 L72 gga04512:ECM-receptor interaction 21 5.79E-04 0.070325 0.667972
    gga04080:Neuroactive ligand-receptor interaction 45 0.004334 0.239385 4.905434
    gga04510:Focal adhesion 32 0.0364 0.540977 34.90982
    gga04010:MAPK signaling pathway 37 0.052973 0.533259 46.75692
    gga04310:Wnt signaling pathway 23 0.097339 0.6588 69.45459
  10 L63 gga04080:Neuroactive ligand-receptor interaction 48 0.001017 0.12119 1.172739
    gga04010:MAPK signaling pathway 38 0.041861 0.595512 39.09871
    gga04510:Focal adhesion 32 0.042927 0.548881 39.87981
    gga04310:Wnt signaling pathway 24 0.069217 0.679767 56.47578
  1. DPI: Days post infection; Count: Number of genes associated with pathway; FDR: False discovery rate. P-value, adjusted p-value and FDR were calculated using default parameters in DAVID [12,13].