Figure 11

Partial conservation of MSCI and PSCR among mouse, dog, and man. A) Walking average of gene expression along chromosome 1 in spermatocytes and round spermatids from dog and mouse. B) Walking average of gene expression along chromosome X in spermatocytes and round spermatids from dog and mouse. PARs are indicated in blue. Centromere positions are shown in dashed gray boxes. C) Boxplot showing median, 25, and 75 percentile of gene expression in the p arm (Xp) and q arm (Xq) of the dog X in spermatocytes and round spermatids compared to boxplots of arbitrarily split autosomes of dog and mouse X chromosomes and autosomes. Asterisks indicate significant difference in gene expression between split autosomes and the X chromosome arms. Plus indicates significant difference between split autosomes and the q arm of the X only. Horizontal red lines indicate significant difference in X-linked gene expression between chromosome arms. D) Venn diagram showing the number of commonly up-regulated (left) and down-regulated (right) X-linked genes in round spermatids compared to spermatocytes in dog, mouse and human. Genes commonly up-regulated or down-regulated in all three species are listed in bold. Down-regulated genes common only to dog and human, not to mouse, are listed with regular characters. Borders of the areas including listed genes are marked in blue.