Figure 5

Sexually dimorphic expression across fetal and adult liver does not show directional consistency. Transcripts were defined as sex dimorphic from RNA-seq data using a genome-wide corrected p-value < 0.1 and −0.5 < log fold change (male/female) > 0.5. X-linked genes are shown in red, Y-linked genes are shown in blue and autosomal genes are shown in green (A) The average log fold change (male/female) for sex dimorphic genes defined from fetal liver (x axis) correlated with expression in the adult liver (y axis); X-linked (ρ = 0.094, p-value = 0.70), autosomal (ρ = 0.068, p-value = 0.19). (B) The log fold change (male/female) for sex dimorphic genes defined from adult liver (x axis) correlated with expression in the fetal liver (y axis) X-linked (ρ = 0.013, p-value = 0.93), autosomal (ρ = −0.042, p-value = 0.13).