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Table 2 Differentially expressed genes in psoriatic lesions compared to healthy controls (LP-C)

From: Transcriptional landscape of psoriasis identifies the involvement of IL36 and IL36RN

Symbol logFC logCPM PValue FDR Entrez Gene Name
OAS2 4.43 7.16 9.26E-70 2.14E-65 2'-5'-oligoadenylate synthetase 2
PLA2G4E 2.55 7.60 2.74E-68 3.16E-64 Phospholipase A2, group IVE
KLK9 5.20 4.01 2.20E-67 1.69E-63 Kallikrein-related peptidase 9
S100A12 9.00 4.41 1.25E-65 7.20E-62 S100 calcium binding protein A12
LCE3E 6.99 4.45 6.02E-65 2.78E-61 Late cornified envelope 3E
TGM1 3.42 6.51 4.94E-61 1.90E-57 Transglutaminase 1
OAS3 2.99 7.25 1.01E-59 3.33E-56 2'-5'-oligoadenylate synthetase 3
PARP9 2.20 7.11 2.80E-59 8.08E-56 Poly (ADP-ribose) polymerase, 9
CRABP2 2.49 5.65 1.99E-57 5.10E-54 Cellular retinoic acid binding protein 2
PLA2G4D 4.33 6.10 3.03E-56 7.01E-53 Phospholipase A2, group IVD
IL1F9 5.64 6.61 2.26E-55 4.74E-52 Interleukin 36, gamma
ALOX12B 3.01 7.30 7.12E-55 1.37E-51 Arachidonate 12-lipoxygenase
SAMD9 3.01 6.23 8.59E-55 1.53E-51 Sterile alpha motif domain
IL1F5 3.59 7.91 1.14E-53 1.87E-50 Interleukin 36 receptor antagonist
C10orf99 6.22 5.44 3.20E-52 4.93E-49 Chrom 10 open reading frame 99
DEFB4A 10.43 6.59 6.30E-52 9.09E-49 Defensin. beta 4A
AKR1B10 6.22 4.39 4.02E-51 5.46E-48 Aldo-keto reductase family 1
PAPL 4.01 4.60 1.56E-50 2.01E-47 Iron/zinc purple acid protein
GLTP 2.01 7.42 5.00E-50 6.08E-47 Glycolipid transfer protein
KDM6B −1.36 11.51 1.48E-49 1.71E-46 Lysine (K)-specific demethylase 6B
KYNU 4.49 4.72 2.54E-48 2.79E-45 Kynureninase
RRM2 2.68 5.47 3.29E-48 3.46E-45 Ribonucleotide reductase M2
ZC3H12A 3.06 4.88 2.30E-47 2.31E-44 Zinc finger CCCH-type cont 12A
SDR9C7 2.70 5.00 6.01E-47 5.79E-44 Short chain dehydrogenase/reductase
HPSE 3.47 4.17 1.31E-46 1.21E-43 Heparanase
APOL6 2.23 6.52 1.91E-46 1.69E-43 Apolipoprotein L, 6
NIPAL4 1.39 9.13 6.90E-46 5.90E-43 NIPA-like domain containing 4
DMD −1.81 7.46 9.69E-46 7.99E-43 Dystrophin
S100A7A 10.02 10.30 2.84E-45 2.26E-42 S100 calcium binding protein A7A
  1. LogFC is fold changes differences in log2 scale and it describes how many times gene expression differs between groups. Positive values indicate up-regulation in psoriasis. LogCPM (log2 counts-per-million) is average gene expression signal in all samples. FDR is genome-wide corrected P-value.