Table 2 Differentially expressed genes in psoriatic lesions compared to healthy controls (LP-C)
From: Transcriptional landscape of psoriasis identifies the involvement of IL36 and IL36RN
Symbol | logFC | logCPM | PValue | FDR | Entrez Gene Name |
|---|---|---|---|---|---|
OAS2 | 4.43 | 7.16 | 9.26E-70 | 2.14E-65 | 2'-5'-oligoadenylate synthetase 2 |
PLA2G4E | 2.55 | 7.60 | 2.74E-68 | 3.16E-64 | Phospholipase A2, group IVE |
KLK9 | 5.20 | 4.01 | 2.20E-67 | 1.69E-63 | Kallikrein-related peptidase 9 |
S100A12 | 9.00 | 4.41 | 1.25E-65 | 7.20E-62 | S100 calcium binding protein A12 |
LCE3E | 6.99 | 4.45 | 6.02E-65 | 2.78E-61 | Late cornified envelope 3E |
TGM1 | 3.42 | 6.51 | 4.94E-61 | 1.90E-57 | Transglutaminase 1 |
OAS3 | 2.99 | 7.25 | 1.01E-59 | 3.33E-56 | 2'-5'-oligoadenylate synthetase 3 |
PARP9 | 2.20 | 7.11 | 2.80E-59 | 8.08E-56 | Poly (ADP-ribose) polymerase, 9 |
CRABP2 | 2.49 | 5.65 | 1.99E-57 | 5.10E-54 | Cellular retinoic acid binding protein 2 |
PLA2G4D | 4.33 | 6.10 | 3.03E-56 | 7.01E-53 | Phospholipase A2, group IVD |
IL1F9 | 5.64 | 6.61 | 2.26E-55 | 4.74E-52 | Interleukin 36, gamma |
ALOX12B | 3.01 | 7.30 | 7.12E-55 | 1.37E-51 | Arachidonate 12-lipoxygenase |
SAMD9 | 3.01 | 6.23 | 8.59E-55 | 1.53E-51 | Sterile alpha motif domain |
IL1F5 | 3.59 | 7.91 | 1.14E-53 | 1.87E-50 | Interleukin 36 receptor antagonist |
C10orf99 | 6.22 | 5.44 | 3.20E-52 | 4.93E-49 | Chrom 10 open reading frame 99 |
DEFB4A | 10.43 | 6.59 | 6.30E-52 | 9.09E-49 | Defensin. beta 4A |
AKR1B10 | 6.22 | 4.39 | 4.02E-51 | 5.46E-48 | Aldo-keto reductase family 1 |
PAPL | 4.01 | 4.60 | 1.56E-50 | 2.01E-47 | Iron/zinc purple acid protein |
GLTP | 2.01 | 7.42 | 5.00E-50 | 6.08E-47 | Glycolipid transfer protein |
KDM6B | −1.36 | 11.51 | 1.48E-49 | 1.71E-46 | Lysine (K)-specific demethylase 6B |
KYNU | 4.49 | 4.72 | 2.54E-48 | 2.79E-45 | Kynureninase |
RRM2 | 2.68 | 5.47 | 3.29E-48 | 3.46E-45 | Ribonucleotide reductase M2 |
ZC3H12A | 3.06 | 4.88 | 2.30E-47 | 2.31E-44 | Zinc finger CCCH-type cont 12A |
SDR9C7 | 2.70 | 5.00 | 6.01E-47 | 5.79E-44 | Short chain dehydrogenase/reductase |
HPSE | 3.47 | 4.17 | 1.31E-46 | 1.21E-43 | Heparanase |
APOL6 | 2.23 | 6.52 | 1.91E-46 | 1.69E-43 | Apolipoprotein L, 6 |
NIPAL4 | 1.39 | 9.13 | 6.90E-46 | 5.90E-43 | NIPA-like domain containing 4 |
DMD | −1.81 | 7.46 | 9.69E-46 | 7.99E-43 | Dystrophin |
S100A7A | 10.02 | 10.30 | 2.84E-45 | 2.26E-42 | S100 calcium binding protein A7A |