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Table 2 Up-regulated genes in SBV or SBVdelNSs infected cells

From: Transcriptome analysis reveals the host response to Schmallenberg virus in bovine cells and antagonistic effects of the NSs protein

Top up-regulated genes

Symbol

Entrez gene name

Fold change (log2)

SBV

delNSsSBV

RSAD2

radical S-adenosyl methionine domain containing 2

1.96

11.518

ISG15

ISG15 ubiquitin-like modifier

1.86

10.886

IFIH1/MDA5

interferon induced with helicase C domain 1

-

9.987

GBP5

guanylate binding protein 5

-

9.837

OAS1

2′-5′-oligoadenylate synthetase 1, 40/46 kDa

2.24

9.818

IFIT2

interferon-induced protein with tetratricopeptide repeats 2

1.06

9.643

IFI27

interferon, alpha-inducible protein 27

-

9.387

ZBP1

Z-DNA binding protein 1

-

9.372

GBP4

guanylate binding protein 4

-

9.354

VCAM1

vascular cell adhesion molecule 1

-

9.287

OAS2

2′-5′-oligoadenylate synthetase 2, 69/71 kDa

2.41

9,.064

IFIT3

interferon-induced protein with tetratricopeptide repeats 3

-

8.87

MX1

myxovirus (influenza virus) resistance 1,

1.45

8.683

XAF1

XIAP associated factor 1

-

8.264

CCL5

chemokine (C-C motif) ligand 5

-

8.081

RTP4

receptor (chemosensory) transporter protein 4

-

8.059

GBP1

guanylate binding protein 1, interferon-inducible

-

7.483

GBP2

guanylate binding protein 2, interferon-inducible

-

6.853

LGALS9

lectin, galactoside-binding, soluble, 9

-

6.571

USP18

ubiquitin specific peptidase 18

-

6.536

CMPK2

cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial

-

6.52

UBA7

ubiquitin-like modifier activating enzyme 7

-

6.15

DDX58

DEAD (Asp-Glu-Ala-Asp) box polypeptide 58

-

6.022

CXCL2

chemokine (C-X-C motif) ligand 2

-

5.946

CYP2J2

cytochrome P450, family 2, subfamily J, polypeptide 2

-

5.936

IFI6

interferon, alpha-inducible protein 6

-

5.807

MCHR1

melanin-concentrating hormone receptor 1

-

5.762

IFIT1

interferon-induced protein with tetratricopeptide repeats 1

-

5.681

HERC6

HECT and RLD domain containing E3 ubiquitin protein ligase family member 6

-

5.612

BATF2

basic leucine zipper transcription factor, ATF-like 2

-

5.483

GNAL

Guanine nucleotide-binding protein G(olf) subunit alpha

1.37

-

RPS3A

ribosomal protein S3A

1.16

-

  1. The table indicates the most up-regulated genes during SBV and SBVdelNSs infection of bovine primary cells at 16 h (compared to uninfected cells). The fold-change is shown in log2 and “-” denotes no fold-change.