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Table 2 Up-regulated genes in SBV or SBVdelNSs infected cells

From: Transcriptome analysis reveals the host response to Schmallenberg virus in bovine cells and antagonistic effects of the NSs protein

Top up-regulated genes
Symbol Entrez gene name Fold change (log2)
SBV delNSsSBV
RSAD2 radical S-adenosyl methionine domain containing 2 1.96 11.518
ISG15 ISG15 ubiquitin-like modifier 1.86 10.886
IFIH1/MDA5 interferon induced with helicase C domain 1 - 9.987
GBP5 guanylate binding protein 5 - 9.837
OAS1 2′-5′-oligoadenylate synthetase 1, 40/46 kDa 2.24 9.818
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 1.06 9.643
IFI27 interferon, alpha-inducible protein 27 - 9.387
ZBP1 Z-DNA binding protein 1 - 9.372
GBP4 guanylate binding protein 4 - 9.354
VCAM1 vascular cell adhesion molecule 1 - 9.287
OAS2 2′-5′-oligoadenylate synthetase 2, 69/71 kDa 2.41 9,.064
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 - 8.87
MX1 myxovirus (influenza virus) resistance 1, 1.45 8.683
XAF1 XIAP associated factor 1 - 8.264
CCL5 chemokine (C-C motif) ligand 5 - 8.081
RTP4 receptor (chemosensory) transporter protein 4 - 8.059
GBP1 guanylate binding protein 1, interferon-inducible - 7.483
GBP2 guanylate binding protein 2, interferon-inducible - 6.853
LGALS9 lectin, galactoside-binding, soluble, 9 - 6.571
USP18 ubiquitin specific peptidase 18 - 6.536
CMPK2 cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial - 6.52
UBA7 ubiquitin-like modifier activating enzyme 7 - 6.15
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 - 6.022
CXCL2 chemokine (C-X-C motif) ligand 2 - 5.946
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2 - 5.936
IFI6 interferon, alpha-inducible protein 6 - 5.807
MCHR1 melanin-concentrating hormone receptor 1 - 5.762
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 - 5.681
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 - 5.612
BATF2 basic leucine zipper transcription factor, ATF-like 2 - 5.483
GNAL Guanine nucleotide-binding protein G(olf) subunit alpha 1.37 -
RPS3A ribosomal protein S3A 1.16 -
  1. The table indicates the most up-regulated genes during SBV and SBVdelNSs infection of bovine primary cells at 16 h (compared to uninfected cells). The fold-change is shown in log2 and “-” denotes no fold-change.