Figure 4From: Fungal artificial chromosomes for mining of the fungal secondary metabolomeA diagram shows the workflow of cryptic SM production. High molecular weight genomic DNA from A. terreus was mechanically sheared and cloned into shuttle AMAI-BAC (or FAC) clones, SM FACs were selected and transformed into A. nidulans, transformants screened for metabolites followed by compound identification and structure elucidation.Back to article page