TY - JOUR AU - Singer, Meromit AU - Pachter, Lior PY - 2015 DA - 2015/05/30 TI - Controlling for conservation in genome-wide DNA methylation studies JO - BMC Genomics SP - 420 VL - 16 IS - 1 AB - A commonplace analysis in high-throughput DNA methylation studies is the comparison of methylation extent between different functional regions, computed by averaging methylation states within region types and then comparing averages between regions. For example, it has been reported that methylation is more prevalent in coding regions as compared to their neighboring introns or UTRs, leading to hypotheses about novel forms of epigenetic regulation. SN - 1471-2164 UR - https://doi.org/10.1186/s12864-015-1604-3 DO - 10.1186/s12864-015-1604-3 ID - Singer2015 ER -