Fig. 7From: A novel termini analysis theory using HTS data alone for the identification of Enterococcus phage EF4-like genome termini (a) IME-EF4 and IME-EFm1 concatemer processing pathways and (b) terminal sequence details. The packaging of concatemeric dsDNA is initiated from the end generated by the initiation cleavage, which then proceeds unidirectionally before being terminated by the termination cleavage. IME-EF4/IME-EFm1 terminases introduce nicks staggered by 9 bp concatemer (highlighted in red) at cosN and melts the strands by its helicase activity after recognition of cosB (●)and cosQ (O) for initiation and termination cleavage, respectivelyBack to article page