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Table 1 QTL Models (phenotypes and explained variance). The table shows the positions for the identified loci (rows) for each phenotype (columns). For each loci the additive component is shown as being either C3H >B6 or C3H <B6 indicating in which genotype the phenotype value is higher. Dominance, if present, is shown by a (D) next to the appropriate parental strain. Finally the variance explained and LOD score (in parentheses) are shown as determined by removing that term from the analysis. Although several of the models involved interactions they are not indicated in this table

From: High-throughput phenotyping and genetic linkage of cortical bone microstructure in the mouse

Chr

Pos (cM)

BMD

Cortical thickness

Cortical thickness variance

Canal density

Lacuna density

Mean lacuna volume

Mean lacuna stretch

1

89.9

C3H (D) >B6, 5.73 (12.77)

      

1

22.3

 

C3H >B6, 4.07 (8.53)

     

1

97.1

 

C3H >B6, 3.42 (7.20)

     

1

59.0

  

C3H >B6, 1.71 (3.13)

    

1

81.5

     

C3H >B6, 2.28 (6.16)

 

3

39.2

  

C3H <B6, 1.81 (3.32)

    

4

52.1

C3H >B6, 4.82 (10.81)

      

5

53.8

     

C3H >B6, 1.68 (4.55)

 

5

68.0

     

C3H >B6 (D), 6.97 (18.11)

 

5

68.2

      

C3H >B6 (D), 3.45 (6.52)

6

20.8

C3H <B6, 3.33 (7.55)

      

6

61.7

C3H (D) >B6, 2.10 (4.80)

      

6

63.4

 

C3H >B6, 1.08 (2.31)

C3H >B6, 2.35 (4.29)

    

6

4.1

    

C3H (D) <B6, 0.53 (1.00)

  

6

18.9

      

C3H <B6 (D), 2.77 (5.25)

7

2.2

C3H >B6, 1.91 (4.38)

      

7

60.6

 

C3H >B6, 4.24 (8.89)

     

7

43.3

     

C3H >B6, 2.60 (7.00)

 

7

1.7

      

C3H (D) <B6, 1.46 (2.80)

8

18.2

     

C3H (D) <B6, 1.85 (5.02)

 

9

12.0

C3H <B6, 3.32 (7.51)

      

9

13.2

   

C3H (D) <B6, 4.15 (7.25)

   

9

40.1

    

C3H <B6, 5.59 (10.26)

  

9

32.2

     

C3H <B6, 4.86 (12.85)

 

10

17.8

    

C3H >B6, 3.88 (7.19)

  

11

45.6

 

C3H >B6, 4.53 (9.47)

     

11

54.1

  

C3H >B6 (D), 1.27 (2.34)

    

11

8.8

      

C3H >B6, 2.38 (4.52)

12

16.2

 

C3H (D) <B6, 1.79 (3.81)

     

12

3.0

    

C3H <B6, 2.19 (4.09)

  

12

3.6

     

C3H <B6, 3.44 (9.20)

 

13

10.3

 

C3H >B6 (D), 5.81 (12.05)

     

13

46.2

      

C3H >B6, 2.25 (4.28)

14

22.1

C3H >B6, 2.17 (4.96)

      

15

21.5

C3H (D) >B6, 2.92 (6.63)

      

15

27.7

     

C3H >B6, 2.36 (6.35)

 

17

4.9

C3H <B6, 4.44 (9.99)

      

17

7.9

  

C3H >B6 (D), 2.65 (4.83)

    

17

45.3

     

C3H <B6, 1.74 (4.72)

 

18

44.5

C3H >B6, 2.80 (6.36)

      

18

15.4

  

C3H (D) <B6, 1.64 (3.00)

    

18

23.5

   

C3H >B6, 3.84 (6.72)

   

18

14.6

     

C3H >B6, 3.16 (8.46)