Fig. 4
From: Reorganization of metastamiRs in the evolution of metastatic aggressive neuroblastoma cells
Modulation of metastamiRs target proteins in MSDACs ex vivo and in metastatic tumors in vivo. Immunoblots showing the expressional modulation of key metastatsis and tumor progression related protein targets of the identified metastamiRs in (a) parental SH-SY5Y cells vs MSDACs under ex vivo conditions and; (b and c) non-metastatic xenograft vs manifold of metastatic tumors from aggressive disease animals in vivo