Table 1 Participant characteristics by study
From: APOL1 G1 genotype modifies the association between HDLC and kidney function in African Americans
| Ā | HUFS | NHAAN | ARIC | |||
|---|---|---|---|---|---|---|
| Ā | Men | Women | Men | Women | Men | Women |
N | 486 | 763 | 220 | 347 | 690 | 1086 |
Age (yrs) | 42.3āĀ±ā12.8 | 41.7āĀ±ā13.1 | 46.4āĀ±ā13.7 | 44.9āĀ±ā13.1 | 53.1āĀ±ā5.9 | 52.3āĀ±ā5.5 |
BMI (kg/m2) | 28.7āĀ±ā7.6 | 31.4āĀ±ā8.9 | 29.3āĀ±ā7.2 | 33.2āĀ±ā9.0 | 27.3āĀ±ā4.7 | 30.1āĀ±ā6.3 |
African Ancestry (%) | 79.9āĀ±ā11.2 | 79.0āĀ±ā11.6 | 79.5āĀ±ā11.1 | 80.4āĀ±ā9.8 | 83.0āĀ±ā11.0 | 83.0āĀ±ā10.9 |
rs73885319 GG (%) | 21 (4.3 %) | 31 (4.1 %) | 25 (11.4 %) | 34 (9.8 %) | 9 (1.3 %) | 27 (2.5 %) |
HDLC (mg/dl) | 50.5āĀ±ā14.9 | 54.7āĀ±ā14.9 | 48.1āĀ±ā15.3 | 53.1āĀ±ā16.8 | 51.6āĀ±ā17.4 | 58.7āĀ±ā17.1 |
rs71785313 ā/ā (%) | 10 (2.1 %) | 18 (2.4 %) | 6 (2.7 %) | 11 (3.2 %) | -- | -- |
2 APOL1 risk alleles (%)1 | 60 (12.5 %) | 89 (12.1 %) | 46 (20.9 %) | 89 (25.7 %) | -- | -- |
eGFR (ml/min/1.73Ā m2) | 106.8āĀ±ā18.8 | 107.7āĀ±ā20.9 | 98.6āĀ±ā20.9 | 100.9āĀ±ā21.4 | 78.2āĀ±ā12.0 | 78.0āĀ±ā11.9 |