From: The venomous cocktail of the vampire snail Colubraria reticulata (Mollusca, Gastropoda)
Protein family | Total contig number | SG contig number | SG logFC | MO contig number | MO logFC | Putative activities | Hypothesized mechanism |
---|---|---|---|---|---|---|---|
vWFA | 177 | 24 | 6.1-16.2 (10.5) | 0 | 0 | antiplatelet | platelet scavenging |
ACE | 85 | 12 | 4.6-16 (10.3) | 1 | 3.5 | vasopressive | conversion of AngI to AngII |
Porins | 62 | 38 | 5.9-12.1 (8.8) | 3 | 8.2-7.1 (7.1) | cytolytic | pore formation |
ShK | 42 | 25 | 5.7-13.5 (8.9) | 0 | 0 | anaesthetic | K+ channel blocking |
PS1 | 41 | 2 | 11.8-14.5 (13.2) | 0 | 0 | anticoagulant | fibrino(geno)lytic, inhibition of coagulation factors |
Meprin | 33 | 8 | 5.1-13 (10.8) | 1 | 7.6 | anticoagulant; tissue degradation | fibrino(geno)lytic |
Kunitz | 27 | 1 | 5.1 | 8 | 6.4-10.1 (8.2) | anticoagulant | inhibition of thrombin and coagulation factors |
CRISPs | 26 | 12 | 7.0-10.6 (9.7) | 0 | 0 | anaesthetic; antiplatelet | ion channel blocking; radical superoxide scavenging |
Turripeptide | 17 | 0 | 0 | 1 | 8.5 | anaesthetic | Gly channel blocking |
ENPP5 | 17 | 4 | 7.3-10.8 (10.2) | 0 | 0 | antiplatelet | production of Ap4A |
ADA | 4 | 4 | 6.9-11.1 (8.9) | 0 | 0 | anaesthetic | removal of adenosine |
CAP-ShK | 3 | 3 | 8.8-10.2 (10.1) | 0 | 0 | anaesthetic | Ca2+ channel blocking |