The Streptomyces leeuwenhoekii genome: de novo sequencing and assembly in single contigs of the chromosome, circular plasmid pSLE1 and linear plasmid pSLE2

Table 1 Putative biosynthetic gene clusters for specialised metabolites

antiSMASH Cluster No.	antiSMASH type descriptor	Position (manually annotated clusters in italics)		Our annotation (based on Ref.)
antiSMASH Cluster No.	antiSMASH type descriptor	From	To	Our annotation (based on Ref.)
1	T1pks	99264	143430
	Not identified	160425	189028	Hygromycin A [11, 44]
2	T1pks	191701	240196
3	T1pks-nrps	324784	392261
4	Nrps	379508	426758
5	T3pks	416888	458084
6	Bacteriocin	572464	582679
7	Terpene	598795	619823
	Not identified	684373	654830	Lasso-peptide 2
8	Nrps	714060	794426
9	Terpene	1056004	1076960
10	T2pks-transatpks-nrps	1075399	1155931	Halogenated polyketide [Razmilic et al.]
11	T1pks-terpene	1211049	1289829	Chaxamycin [Castro et al.]
12	T1pks	1497127	1544539
13	Terpene	1624097	1645110
14	T1pks-siderophore	1776281	1833813
15	Terpene	1972277	1994487
16	Bacteriocin	2013690	2025087
17	Siderophore	2293580	2305424	Highly conserved
18	Nrps-t1pks	2668194	2719415
19	T3pks	2937137	2978264
20	Terpene	3056325	3058819	Albaflavenone [45, 46]
	Not identified	3560196	3564842	Lasso-peptide 1
21	Siderophore	5237176	5244356	Desferrioxamine E [11, 47, 48]
22	Melanin	5330379	5340933
23	Amglyccycl-butyrolactone	5385171	5417416
24	Ectoine	6176293	6186691
25	Other	6710095	6751819
26	T3pks	6822979	6864043
27	T1pks	7141058	7240871	Chaxalactin [11, Castro et al.]
28	T1pks	7355977	7439461
29	Other	7486047	7529121
30	Terpene-t2pks	7530162	7588405
31	Terpene	7744176	7768730
	Not identified	pSLE2 103389	pSLE2 105999	Lasso-peptide 3

ISSN: 1471-2164