Gene Symbol | Loading | Z-score | Â |
---|---|---|---|
HLF | 1.059 | 3.690 | Inhibitor of cell death response [PMID:23415677] |
ZBTB16 | 1.039 | 3.621 | Â |
HOPX | 1.022 | 3.558 | Controlling differentiation-dependent genes [PMID:20226564] |
EGR3 | 0.999 | 3.477 | Â |
ID4 | 0.986 | 3.436 | Lack of the protein in parakeratotic cells at upper skin layer [PMID:21663940] |
MNDA | 0.968 | 3.369 | Â |
HCLS1 | 0.947 | 3.297 | Â |
SOX5 | 0.947 | 3.295 | Genes coding SOX5 binding sites at the promoters were PC1 positive correlation (V$SOX5_01; q-value FDR ~ 0) |
SOX21 | 0.937 | 3.261 | Master regulator of hair shaft cuticle differentiation [PMID:19470461] |
ETV7 | 0.928 | 3.227 | Â |
POU3F1 | 0.920 | 3.200 | Transactivator for FLG (a.k.a. profilaggrin; PC1 positive correlation, Local- FDR = 7.34 × 10-4; [PMID:10809764]) |
POU2F3 | 0.906 | 3.151 | 10-4; [PMID:10809764] & [PMID:7682011]); repressor for KRT14 (PC1 negative correlation, Local-FDR ~ 0; [PMID:11429405]) |