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Table 5 Most significant gene sets enriched in PC2 correlating genes. (a) Table is a subset of gene sets (ten out of 23) significantly (FDR q-value < 1 %) enriched in PC2 positively correlating genes, which were upregulated in EKCs, by PC-GSEA (for full data, see Additional file 10: Table S7). (b) Table is gene sets significantly enriched in PC2 negatively correlating genes, which were upregulated in HaCaTs. SIZE is number of genes belonging the gene set. NES is normalized enrichment score

From: Gene expression analysis of skin grafts and cultured keratinocytes using synthetic RNA normalization reveals insights into differentiation and growth control

Name SIZE NES FDR q-val
(a)    
PUJANA_BRCA_CENTERED_NETWORK 117 1.909 0.00492
ZHANG_TLX_TARGETS_UP 89 1.875 0.00885
BURTON_ADIPOGENESIS_PEAK_AT_16H 40 1.873 0.00590
PUJANA_XPRSS_INT_NETWORK 168 1.869 0.00467
ZHANG_TLX_TARGETS_36HR_DN 185 1.868 0.00394
EGUCHI_CELL_CYCLE_RB1_TARGETS 23 1.856 0.00476
REACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM 52 1.846 0.00436
ABRAMSON_INTERACT_WITH_AIRE 44 1.845 0.00394
GOLUB_ALL_VS_AML_UP 24 1.841 0.00383
ZHANG_TLX_TARGETS_60HR_DN 275 1.839 0.00374
(b)    
MIKKELSEN_ES_HCP_WITH_H3K27ME3 35 2.441 0.00000
REACTOME_XENOBIOTICS 15 2.345 0.00851