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Fig. 6 | BMC Genomics

Fig. 6

From: The human cardiac and skeletal muscle proteomes defined by transcriptomics and antibody-based profiling

Fig. 6

Immunohistochemical staining of proteins elevated in both cardiac and skeletal muscle. a Examples of four proteins related to muscular contraction (MYH7, MYL3, TNNC1 and TPM3), in skeletal muscle higher expressed in type I muscle fibers. b Examples of four proteins related to calcium transport and storage (CAMK2B, CASQ1, HRC and SRL). c Examples of four proteins related to metabolism and myofibrillar organization (CKM, PGAM2, LDB3 and MURC). LDB3 was restricted to Z-lines of cardiac muscle fibers while more homogeneous in skeletal muscle. MURC showed distinct expression of sarcolemma in both cardiac and skeletal muscle. d Examples of four proteins with unknown function in cardiac and skeletal muscle, with ADSSL1 showing distinct nuclear staining, HHATL and C1ORF170 displaying cytoplasmic positivity, and SPTB revealing distinct immunoreactivity in sarcolemma, accompanied with positivity in erythrocytes

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