Fig. 1

Infection of adult flies with Heterorhabditis nematodes or their Photorhabdus bacteria elicits distinct transcriptomic profiles. a Transcriptome summary (number of reads and percentage mapped to the D. melanogaster genome) from flies infected by Heterorhabditis axenic or symbiotic nematodes, or Photorhabdus bacteria at 12 and 30 h post-infection. b Differential gene transcription (upregulated/downregulated genes) in flies at 12 h and 30 h post-infection with Heterorhabditis axenic or symbiotic nematodes, or Photorhabdus bacteria alone. c CUFFLINKS analysis of differentially expressed transcripts between the 12 and 30 h time-points in flies infected by Heterorhabditis axenic or symbiotic nematodes, or Photorhabdus bacteria alone. d Venn diagrams showing the number of Drosophila genes that are differentially expressed (upregulated or downregulated) at 12 h only or at 30 h only or at both time-points after infection with Heterorhabditis axenic or symbiotic nematodes, or their Photorhabdus bacteria alone. Expression patterns are indicated (UP/UP: gene upregulation at both 12 and 30 h, DOWN/UP: gene downregulation at 12 h and upregulation at 30 h, DOWN/DOWN: gene downregulation at both time-points, UP/DOWN: gene upregulation at 12 h and downregulation at 30 h)