Fig. 6

Schematic representation of an imprinted genomic segment on the telomeric arm of ovine chromosome 18. The genomic region highlights multiple miRNA many of which were identified as differentially expressed in Cluster 5. Blue, paternally expressed protein encoding genes. Pink, maternally expressed noncoding RNA. The central region contains a number of maternally expressed miRNA including a large cluster designated MIRG. MEG8 contains a large cluster of snoRNA while MEG3 is a long noncoding RNA. RTL1AS transcribes a noncoding RNA containing five miRNA, which are known to cause RISC mediated cleavage of the sense protein encoding gene RTL1. All maternally expressed genes are transcribed in the same direction