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Fig. 4 | BMC Genomics

Fig. 4

From: Analysis of the TGFβ-induced program in primary airway epithelial cells shows essential role of NF-κB/RelA signaling network in type II epithelial mesenchymal transition

Fig. 4

Transcription factor-target gene topological analysis. Hierarchical clustering analysis was conducted on 109 transcription factors (gene names of the enriched transcription factors from 47 experiments are shown in columns) and DEGs associated with EMT using the Euclidean distance measure and the Ward. D2 linkage function. Variance, Skewness, and Kurtosis dendrogram results were compared to 1000 random permutations of the data. Three significant clusters, labeled A, B and C are identified at top. The three clusters were highly significant (p < 0.001)

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