Table 4 Significantly enriched human transcription factors for upregulated genes in the EMT process. The enriched transcription factors (TFs) were inferred by comparing ChIP-Seq or ChIP-chip identified target genes (TGs) of each TF with the upregulated DEGs in the EMT process. The enriched TFs were sorted according to the enriched fold ratios

TRIM28

21343339

85

21

3.9

1.8E-05

HEK293

ESR1

21235772

213

36

2.7

4.8E-04

MCF-7

CLOCK

20551151

398

58

2.3

2.3E-05

293 T

ESR2

21235772

392

57

2.3

9.1E-07

MCF-7

SMAD3

21741376

1074

144

2.1

1.4E-06

HESC

SOX2

20726797

2060

275

2.1

<3.45E-14

SW620

RELA

24523406

1147

152

2.1

<3.45E-14

A549

BACH1

22875853

1183

150

2

<3.45E-14

HELA-AND-SCP4

GATA1

19941826

700

84

1.9

3.8E-14

K562

TP53

18474530

734

88

1.9

4.4E-06

U2OS

GATA2

21666600

634

75

1.9

2.1E-06

HMVEC

PAX3-FKHR

20663909

975

115

1.9

4.8E-05

RHABDOMYOSARCOMA

SMAD4

21741376

2032

237

1.8

2.4E-08

HESC

DROSHA

22980978

441

51

1.8

<3.45E-14

HELA

ZNF217

24962896

1400

160

1.8

8.7E-03

MCF7

NFE2L2

22581777

508

58

1.8

4.7E-11

LYMPHOBLASTOID

EOMES

21245162

861

98

1.8

3.7E-03

HESC

SMAD2

18955504

1643

184

1.8

4.1E-06

HaCaT

SMAD3

18955504

1643

184

1.8

3.8E-12

HaCaT

NR3C1

21868756

1023

111

1.7

3.8E-12

MCF10A

DNAJC2

21179169

803

87

1.7

6.1E-06

NT2

EGR1

20690147

5216

549

1.7

2.4E-04

ERYTHROLEUKEMIA

SOX2

21211035

2830

288

1.6

<3.45E-14

LN229_GBM

GATA2

19941826

1727

175

1.6

<3.45E-14

K562

MYC

19915707

1793

177

1.6

8.5E-08

AK7

AR

19668381

2958

291

1.6

5.0E-07

PC3

ATF3

23680149

1995

193

1.5

8.8E-13

GBM1-GSC

SMAD4

21799915

2302

220

1.5

4.3E-07

A2780

GATA1

21571218

2388

228

1.5

7.2E-08

MEGAKARYOCYTES