Transcriptional response of Atlantic salmon families to Piscirickettsia salmonis infection highlights the relevance of the iron-deprivation defence system

Table 2 Functional annotation of common probes significantly up- or down-regulated in LS and HS groups of families

Up-regulated in LS and HS families
^aOntology ID	^bOntology Source	^cOntology Term	^dOntology Levels	^eNumber of genes
GO:0000226	GO_BiologicalProcess	microtubule cytoskeleton organization	[3, 6]	8
GO:0019318	GO_BiologicalProcess	hexose metabolic process	[5, 6]	8
GO:0071310	GO_BiologicalProcess	cellular response to organic substance	[4]	11
GO:0051603	GO_BiologicalProcess	proteolysis involved in cellular protein catabolic process	[5, 6]	17
KEGG:00190	KEGG	oxidative phosphorylation	[−1]	22
KEGG:04142	KEGG	lysosome	[−1]	10
KEGG:04145	KEGG	phagosome	[−1]	11
KEGG:05132	KEGG	Salmonella infection	[−1]	7
KEGG:04620	KEGG	Toll-like receptor signaling pathway	[−1]	9
REACTOME:2756221	REACTOME	metabolism of lipids and lipoproteins	[−1]	26
Down-regulated in LS and HS families
^aOntology ID	^bOntology Source	^cOntology Term	^dOntology Levels	^eNumber of genes
GO:0006325	GO_BiologicalProcess	chromatin organization	[6]	7
GO:0006461	GO_BiologicalProcess	protein complex assembly	[4, 5]	8
GO:0030097	GO_BiologicalProcess	hemopoiesis	[4–6]	10
GO:0042981	GO_BiologicalProcess	regulation of apoptotic process	[5, 6]	11
KEGG:00480	KEGG	Glutathione metabolism	[−1]	8
REACTOME:2756367	REACTOME	Phospholipid metabolism	[−1]	10
REACTOME:2756199	REACTOME	Glycolysis	[−1]	5
REACTOME:2756244	REACTOME	mRNA Splicing - Major Pathway	[−1]	13
REACTOME:2756574	REACTOME	Eukaryotic Translation Elongation	[−1]	56

^aOntology accession numbers (ID)
^bOntology Source, Biological Process (GO), KEGG and Reactome
^cOntology Term and
^dOntology Level associated
^eNumber of genes found in a given ontology category within the analysed list of target probes

ISSN: 1471-2164