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Table 3 Functional annotation of genes differentially expressed between LS and HS in response to P. salmonis infection

From: Transcriptional response of Atlantic salmon families to Piscirickettsia salmonis infection highlights the relevance of the iron-deprivation defence system

Up-regulated in LS families but not modulated in HS Families

  

aOntology ID

bOntology Source

cOntology Term

dOntology Levels

eNumber of genes

GO:0016052

GO_BiologicalProcess

carbohydrate catabolic process

[3, 4]

9

GO:0030036

GO_BiologicalProcess

actin cytoskeleton organization

[3, 6]

12

GO:0016570

GO_BiologicalProcess

histone modification

[6, 9]

4

REACTOME:2756220

REACTOME

Fatty acid, triacylglycerol, and ketone body metabolism

[−1]

11

REACTOME:2756441

REACTOME

Innate Immune System

[−1]

15

Down-regulated in LS families but not modulated in HS Families

  

aOntology ID

bOntology Source

cOntology Term

dOntology Levels

eNumber of genes

GO:0006413

GO_BiologicalProcess

translational initiation

[2, 5, 6]

6

GO:0006935

GO_BiologicalProcess

chemotaxis

[3, 4]

6

GO:0006875

GO_BiologicalProcess

cellular metal ion homeostasis

[6, 8]

6

KEGG:04150

KEGG

mTOR signaling pathway

[−1]

6

KEGG:04070

KEGG

Phosphatidylinositol signaling system

[−1]

6

KEGG:04650

KEGG

Natural killer cell mediated cytotoxicity

[−1]

6

REACTOME:2756528

REACTOME

Platelet activation, signaling and aggregation

[−1]

17

Up-regulated in LS families and Down-regulated in HS Families

  

aOntology ID

bOntology Source

cOntology Term

dOntology Levels

eNumber of genes

GO:0044262

GO_BiologicalProcess

Cellular carbohydrate metabolic process

[3, 4]

16

GO:0007010

GO_BiologicalProcess

cytoskeleton organization

[5]

10

GO:0006457

GO_BiologicalProcess

protein folding

[5]

12

GO:0015992

GO_BiologicalProcess

proton transport (ATP synthesis)

[4–7]

8

GO:0005506

GO_MolecularFunction

iron ion binding

[6]

12

KEGG:00980

KEGG

Metabolism of xenobiotics by cytochrome P450

[−1]

4

REACTOME:2756314

REACTOME

Adaptive Immune System

[−1]

21

REACTOME:2757180

REACTOME

Class I MHC mediated antigen processing & presentation

[−1]

12

REACTOME:2757144

REACTOME

Endosomal Sorting Complex Required For Transport (ESCRT)

[−1]

6

REACTOME:2756315

REACTOME

Immune System

[−1]

34

REACTOME:2756204

REACTOME

Metabolism of amino acids and derivatives

[−1]

15

REACTOME:2756598

REACTOME

Post-translational protein modification

[−1]

8

REACTOME:2756873

REACTOME

Regulation of Apoptosis

[−1]

9

  1. aOntology accession numbers (ID)
  2. bOntology Source, Biological Process (GO), KEGG and Reactome
  3. cOntology Term and
  4. dOntology Level associated
  5. eNumber of genes found in a given ontology category within the analysed list of target probes