Fig. 4

Correlation networks of changes in gene expression patterns and microbiota composition: Blue nodes represent genes and the pink ones represent bacterial groups; pink nodes with a cyan boundary are nodes common in the three networks. The edges represent positive (green) and negative (red) correlation between a gene and a bacterial group. Networks (a), (b) and (c) were built by correlating the gene lists OnlyTr1, Tr1&Tr2 and OnlyTr2 respectively with the 46 microbial groups resulting from the regression analysis. All the nodes (bacterial groups and genes) have a significantly different expression profile in time or treatment compared to the control. High resolution images of the individual networks are given as Additional file 10: Figure S10, Additional file 8: Figure S11 and Additional file 12: Figure S12