Fig. 6

Chromosomal regions with elevated |iHS| values within the combined Ghana population (shaded on chromosome bars), and within each of the local populations (Kintampo shown above and Navrongo below the chromosome bars). Red shading indicates windows containing two or more SNPs within the top 0.1 % of the expected distribution (|iHS| > 3.29) and at least 1 SNP with a |iHS| value > 5. Blue shading indicates windows containing two or more SNPs with |iHS| > 3.29 but none having a value > 5. The regions, and genes within them, are listed in Additional file 1: Table S3. The location of four drug resistance genes mentioned in the text are shown with green markers: dhfr (chr 4), mdr1 (chr 5), crt (chr 7) and dhps (chr 8). Asterisks show the positions of three elevated |iHS| windows for which the Rsb analysis (Fig. 7) indicated stronger evidence of selection in one or other of the two populations