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Table 1 Summary of Gene Ontology Analysis of differentially expressed gene lists. The analysis is based on D. melanogaster orthologs matching honey bee genes that were significantly differentially expressed between treatment groups. Only GO terms and KEGG pathways that were significantly overrepresented (medium stringency, P-value < 0.05) are shown in the table. Benjamini corrections for multiple testing are provided alongside corresponding P-values

From: RNA-sequencing elucidates the regulation of behavioural transitions associated with the mating process in honey bee queens

  Category Term Genes P-Value Benjamini
mated vs. virgin   carbohydrate metabolic process 30 3.33E-05 0.022
  organic acid metabolic process 27 1.79E-04 0.076
  amine metabolic process 26 1.00E-03 0.209
  defense response 11 0.009 0.778
  sensory perception 15 0.011 0.782
  melanization defense response 3 0.012 0.764
biological process cellular amino acid metabolic process 16 0.015 0.76
  fatty acid metabolic process 7 0.015 0.737
  innate immune response 7 0.015 0.737
  carbohydrate catabolic process 8 0.017 0.752
  tissue development 30 0.026 0.805
  detection of stimulus 8 0.04 0.805
  sodium ion transport 6 0.041 0.794
cellular component myofibril 5 0.002 0.035
  membrane part 81 0.003 0.046
  proteinaceous extracellular matrix 7 0.006 0.071
  plasma membrane 39 0.009 0.093
  cofactor binding 19 7.91E-05 0.022
  monooxygenase activity 12 0.002 0.151
  lipase activity 10 0.004 0.214
  FAD binding 8 0.005 0.227
  vitamin binding 10 0.008 0.259
molecular function sugar transmembrane transporter activity 5 0.014 0.29
  transcription factor activity 23 0.018 0.325
  receptor activity 27 0.018 0.318
  transforming growth beta receptor binding 3 0.023 0.336
  identical protein binding 11 0.03 0.368
  sulfate transmembrane transporter activity 3 0.037 0.424
metabolic pathways Starch and sucrose metabolism 7 0.003 0.081
  Glycolysis / Gluconeogenesis 7 0.004 0.061
  Retinol metabolism 5 0.006 0.058
  Arginine and proline metabolism 7 0.006 0.051
  beta-Alanine metabolism 5 0.013 0.087
  Lysine ddegradation 5 0.05 0.192
mated vs. CO2 biological processes aromatic amino acid family process 5 0.003 0.757
  sensory perception 11 0.024 0.995
  monocarboxylic acid metabolic process 7 0.031 0.992
  tissue development 22 0.032 0.987
  response to organic substance 8 0.044 0.992
cellular component membrane 70 1.00E-03 0.014
  muscle myosin complex 3 0.004 0.053
  extracellular region part 8 0.032 0.255
molecular function sugar transmembrane transporter activity 5 0.006 0.222
  transporter activity 33 0.007 0.246
  retinal binding 3 0.018 0.394
  lipase activity 6 0.033 0.545
  olfactory receptor activity 5 0.037 0.551
CO2 vs. virgin biological process cognition 7 0.004 0.105
cellular component rhabdomere 4 1.00E-03 0.01
  membrane 21 0.001 0.012
  cell projection 5 0.004 0.039
  integral to membrane 12 0.056 0.333
molecular function monooxygenase activity 5 3.09E-04 0.054