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Fig. 4 | BMC Genomics

Fig. 4

From: Putative type 1 thymidylate synthase and dihydrofolate reductase as signature genes of a novel bastille-like group of phages in the subfamily Spounavirinae

Fig. 4

Phamily circles connecting 27 type 1 thymidylate synthase (TS1) gene products in 26 phages (pham 363, a), 26 dihydrofolate reductase (DHFR) gene products in 26 phages (pham 369, b), 21 DNA segregation ATPase FtsK/SpoIIIE gene products in 21 phages (pham 473, c) and), 23 metallo-beta-lactamase gene products in 23 phages (pham 484, d). Phamilies were created when gene products exhibited E-values smaller than 1 × 10−50 or greater than 32.5 % identity with at least one other gene product in the pham. Phage Bobb encodes two thymidylate synthase homologs (gp221 and gp223) that belong to pham 363 (See Fig. 5 and the text for more details)

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