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Fig. 2 | BMC Genomics

Fig. 2

From: Infectious hematopoietic necrosis virus (IHNV) persistence in Sockeye Salmon: influence on brain transcriptome and subsequent response to the viral mimic poly(I:C)

Fig. 2

Overview of microarray analysis in brain of Sockeye Salmon. a) A two-way ANOVA (p ≤ 0.01) using expression data of the six groups naïve, survivors, carriers with and without poly(I:C) injection was performed. The IHNV status is indicated for each group. All samples (n) were collected 3 d post injection, i.e. 274 d post challenge (dpc), except for 2 carriers that were sampled 278 dpc. b) Venn diagram of probes affected by IHNV status, poly(I:C)-injection and interaction of both factors. Numbers in parentheses indicate numbers of probes retained after a fold change (FC) cut-off of ≥ 1.5. One asterisk (*) indicates that all interaction probes were removed from main effect lists to analyze separately. Two asterisks (**) refer to the number of probes used as input for k-means clustering shown in Fig. 3. c) Venn diagram of fold change-filtered up- and down-regulated probes affected by IHNV status that were separated into survivor- and carrier-relevant probes

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