Fig. 2

Comparative transcriptome investigation of Wt and Nr2e1 ^frc/frc embryos yielded hundreds of candidate-differentially-regulated genes. a Details of the number of differentially abundant tags (increased or decreased) and the corresponding number of genes between Wt and Nr2e1 ^frc/frc embryos at each time point. In the exceptional case of a gene having both a significantly up and down tag, it was counted in both categories. Column one presents the direction of change; column two, the embryonic day of tissue harvest; column three, the number of tags that had significantly different counts between Wt and Nr2e1 ^frc/frc embryos; column four, the number of tags having significant different counts that mapped to genes found in the Ensembl (v66) and Refseq (v52) gene collections; and column five, the number of Refseq genes mapped by the corresponding tags. b The Venn diagram presents the number of up- and down-regulated genes that were exclusive or shared at each embryonic day (E13.5, E15.5, and E17.5). Bracketed numbers correspond to the total of differentially-regulated genes between Wt and Nr2e1 ^frc/frc embryos at the corresponding time point