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Fig. 6 | BMC Genomics

Fig. 6

From: Combined serial analysis of gene expression and transcription factor binding site prediction identifies novel-candidate-target genes of Nr2e1 in neocortex development

Fig. 6

Lhx2 contains enriched clusters of NR2E1 and SOX9 binding sites in highly conserved regions. Presented is the ~17 kb of genomic sequence 5′ to, and surrounding, the Lhx2 transcription start site. NR2E1 binding sites are indicated in black, and SOX9 binding sites are indicated in red. NR2E1 binding site coordinates were derived from the position-weight matrix (PWM) described in the current manuscript; SOX9 binding sites coordinates were derived from the PWM stored in the JASPAR database (http://jaspar.binf.ku.dk/cgi-bin/jaspar_db.pl). Conservation, alignment of 100 vertebrate species from the University of California, Santa Cruz genome browser (UCSC: http://genome.ucsc.edu/); thick horizontal line, first exon of Lhx2; arrow, transcription start site and sense

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