Fig. 4
Divergence with respect to protein families. a Venn diagrams of protein families (≥10 proteins) with a significant expansion or contraction (right and left circles, respectively). Top: the analysis based on 17 insect proteomes. A total of 655 SSF (species-specific families) were significantly expanded in at least one species. 51 SSF were significantly contracted and 46 families intersected (i.e., at least one species was expanded and at least one contracted). Bottom: the analysis based on 18 Arthropod proteomes, 17 insects and a proteome of D. pulex. b Ratios of SSF that belong to unified set of Pfam annotations (i.e., high-level functionality) relative to all annotated SSF. The analysis for TNAP is illustrated for each of the species. Correlation lines and calculated coefficients are shown. c Histogram of the number of proteins that belong to TNAP for each species. d Identical analysis as in (b) for the unified functionality of membrane receptors (MR)