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Table 1 Largest families, associated Pfam keywords and family specificity

From: Trends in genome dynamics among major orders of insects revealed through variations in protein families

# proteins

# insects

Pfam ID

Pfam name

# TPa

# FPb

# gainc

Spec.

4952

18

PF13465

Zinc-finger double domain

3150

1343

459

0.701

3857

18

PF00069

Protein kinase domain

2954

809

94

0.785

2912

18

PF00089

Trypsin

2895

0

17

1.000

2646

18

PF00400

WD domain, G-beta repeat

2415

37

194

0.985

2240

18

PF07679

Immunoglobulin I-set domain

1391

632

217

0.688

1940

18

PF13855

Leucine rich repeat

1467

323

150

0.820

1860

18

PF12796

Ankyrin repeats (3 copies)

1580

165

115

0.905

1749

18

PF00067

Cytochrome P450

1694

0

55

1.000

1721

18

PF00076

RNA recognition motif. (RRM, RBD, RNP)

1520

125

76

0.924

1667

18

PF00379

Insect cuticle protein

1599

1

67

0.999

1647

18

PF00046

Homeobox domain

1400

147

100

0.905

1630

17

PF02949

7tm Odorant receptor

1507

0

123

1.000

1559

18

PF00071

Ras family

1082

445

32

0.709

1529

18

PF00001

7 tm receptor (rhodopsin family)

1417

43

69

0.971

1160

18

PF00651

BTB/POZ domain

1076

46

38

0.959

1100

18

PF00083

Sugar (and other) transporter

973

105

22

0.903

  1. a TP True positives, b FP False positives, c gain unannotated proteins, Spec. specificity