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Table 1 Most significant DEGs between PABs and SABs

From: Cell cycle control, DNA damage repair, and apoptosis-related pathways control pre-ameloblasts differentiation during tooth development

Gene Symbol Description Fold-change p-value FDR
Genes up-regulated in PAB    
TRPA1 transient receptor potential cation channel, subfamily A, member 1 20.22 1.58E-11 3.17E-07
WEE1 WEE1 homolog (S. pombe) 15.47 2.78E-03 6.62E-02
ETV1 ets variant 1 15.36 2.57E-09 1.43E-05
HIST1H2BM histone cluster 1, H2bm 14.79 7.93E-09 3.30E-05
SPC25 SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae) 13.44 1.18E-09 9.82E-06
FAM177B family with sequence similarity 177, member B 11.90 4.67E-08 8.64E-05
CDKN3 cyclin-dependent kinase inhibitor 3 11.83 6.02E-06 1.63E-03
FAM111B family with sequence similarity 111, member B 11.67 5.55E-09 2.64E-05
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 11.41 3.36E-07 2.95E-04
BIRC5 baculoviral IAP repeat containing 5 10.78 3.03E-06 1.08E-03
NUSAP1 nucleolar and spindle associated protein 1 10.78 1.90E-08 5.74E-05
ETV5 ets variant 5 10.48 1.42E-07 1.90E-04
TOP2A topoisomerase (DNA) II alpha 170 kDa 10.48 6.66E-08 1.06E-04
BRIP1 BRCA1 interacting protein C-terminal helicase 1 10.41 1.78E-06 7.79E-04
PLK4 polo-like kinase 4 10.02 5.30E-05 6.03E-03
CENPF centromere protein F, 350/400 kDa (mitosin) 9.81 6.31E-08 1.05E-04
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 9.39 8.76E-06 2.07E-03
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) 9.33 6.40E-10 7.10E-06
SNORD30 small nucleolar RNA, C/D box 30 9.13 8.45E-04 3.23E-02
FAM9A family with sequence similarity 9, member A 9.12 1.29E-08 4.76E-05
RAD51AP1 RAD51 associated protein 1 8.96 7.47E-07 4.69E-04
CENPK centromere protein K 8.63 3.69E-07 3.15E-04
DTL denticleless homolog (Drosophila) 8.60 2.70E-06 1.01E-03
KIF11 kinesin family member 11 8.53 1.59E-07 1.99E-04
HELLS helicase, lymphoid-specific 8.32 2.52E-07 2.37E-04
SEMA3E sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E 8.18 1.96E-04 1.35E-02
Genes up-regulated in SAB    
MMP20 matrix metallopeptidase 20 -26.41 9.20E-07 4.91E-04
SLC15A1 solute carrier family 15 (oligopeptide transporter), member 1 -21.58 6.42E-06 1.72E-03
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 -18.49 1.24E-05 2.53E-03
RGS13 regulator of G-protein signaling 13 -15.51 7.68E-06 1.94E-03
SPHKAP SPHK1 interactor, AKAP domain containing -11.86 3.14E-05 4.59E-03
ENAM enamelin -10.78 3.16E-03 7.06E-02
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) -10.14 4.38E-06 1.34E-03
LAMC2 laminin, gamma 2 -10.07 2.56E-05 4.10E-03
NMNAT2 nicotinamide nucleotide adenylyltransferase 2 -10.02 1.47E-05 2.78E-03
DSPP dentin sialophosphoprotein -9.32 1.41E-02 1.58E-01
FAM20A family with sequence similarity 20, member A -9.13 8.58E-07 4.91E-04
DMP1 dentin matrix acidic phosphoprotein 1 -8.73 4.71E-04 2.29E-02