Skip to main content

Table 1 Most significant DEGs between PABs and SABs

From: Cell cycle control, DNA damage repair, and apoptosis-related pathways control pre-ameloblasts differentiation during tooth development

Gene Symbol

Description

Fold-change

p-value

FDR

Genes up-regulated in PAB

   

TRPA1

transient receptor potential cation channel, subfamily A, member 1

20.22

1.58E-11

3.17E-07

WEE1

WEE1 homolog (S. pombe)

15.47

2.78E-03

6.62E-02

ETV1

ets variant 1

15.36

2.57E-09

1.43E-05

HIST1H2BM

histone cluster 1, H2bm

14.79

7.93E-09

3.30E-05

SPC25

SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)

13.44

1.18E-09

9.82E-06

FAM177B

family with sequence similarity 177, member B

11.90

4.67E-08

8.64E-05

CDKN3

cyclin-dependent kinase inhibitor 3

11.83

6.02E-06

1.63E-03

FAM111B

family with sequence similarity 111, member B

11.67

5.55E-09

2.64E-05

DLGAP5

discs, large (Drosophila) homolog-associated protein 5

11.41

3.36E-07

2.95E-04

BIRC5

baculoviral IAP repeat containing 5

10.78

3.03E-06

1.08E-03

NUSAP1

nucleolar and spindle associated protein 1

10.78

1.90E-08

5.74E-05

ETV5

ets variant 5

10.48

1.42E-07

1.90E-04

TOP2A

topoisomerase (DNA) II alpha 170 kDa

10.48

6.66E-08

1.06E-04

BRIP1

BRCA1 interacting protein C-terminal helicase 1

10.41

1.78E-06

7.79E-04

PLK4

polo-like kinase 4

10.02

5.30E-05

6.03E-03

CENPF

centromere protein F, 350/400 kDa (mitosin)

9.81

6.31E-08

1.05E-04

EFEMP1

EGF containing fibulin-like extracellular matrix protein 1

9.39

8.76E-06

2.07E-03

ASPM

asp (abnormal spindle) homolog, microcephaly associated (Drosophila)

9.33

6.40E-10

7.10E-06

SNORD30

small nucleolar RNA, C/D box 30

9.13

8.45E-04

3.23E-02

FAM9A

family with sequence similarity 9, member A

9.12

1.29E-08

4.76E-05

RAD51AP1

RAD51 associated protein 1

8.96

7.47E-07

4.69E-04

CENPK

centromere protein K

8.63

3.69E-07

3.15E-04

DTL

denticleless homolog (Drosophila)

8.60

2.70E-06

1.01E-03

KIF11

kinesin family member 11

8.53

1.59E-07

1.99E-04

HELLS

helicase, lymphoid-specific

8.32

2.52E-07

2.37E-04

SEMA3E

sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E

8.18

1.96E-04

1.35E-02

Genes up-regulated in SAB

   

MMP20

matrix metallopeptidase 20

-26.41

9.20E-07

4.91E-04

SLC15A1

solute carrier family 15 (oligopeptide transporter), member 1

-21.58

6.42E-06

1.72E-03

SLC7A11

solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11

-18.49

1.24E-05

2.53E-03

RGS13

regulator of G-protein signaling 13

-15.51

7.68E-06

1.94E-03

SPHKAP

SPHK1 interactor, AKAP domain containing

-11.86

3.14E-05

4.59E-03

ENAM

enamelin

-10.78

3.16E-03

7.06E-02

HPGD

hydroxyprostaglandin dehydrogenase 15-(NAD)

-10.14

4.38E-06

1.34E-03

LAMC2

laminin, gamma 2

-10.07

2.56E-05

4.10E-03

NMNAT2

nicotinamide nucleotide adenylyltransferase 2

-10.02

1.47E-05

2.78E-03

DSPP

dentin sialophosphoprotein

-9.32

1.41E-02

1.58E-01

FAM20A

family with sequence similarity 20, member A

-9.13

8.58E-07

4.91E-04

DMP1

dentin matrix acidic phosphoprotein 1

-8.73

4.71E-04

2.29E-02