Table 5 Gene Ontology enrichment (Biological Process) of predicted marker genes for the examined tissues
GO ID | GO | p-value | Expected count | Gene count | Size |
|---|---|---|---|---|---|
Midbrain | |||||
GO:0007409 | axonogenesis | 4.49×10−22 | 46.71 | 118 | 489 |
GO:0010975 | regulation of neuron projection development | 5.58×10−20 | 21.4 | 70 | 224 |
GO:0006836 | neurotransmitter transport | 3.93×10−18 | 12.42 | 49 | 130 |
GO:0051969 | regulation of transmission of nerve impulse | 9.65×10−16 | 19.11 | 59 | 200 |
GO:0016358 | dendrite development | 6.24×10−13 | 12.51 | 42 | 131 |
Heart atrium | |||||
GO:0006941 | striated muscle contraction | 3.12×10−27 | 3.82 | 37 | 97 |
GO:0060047 | heart contraction | 3.34×10−27 | 5.76 | 44 | 146 |
GO:0048738 | cardiac muscle tissue development | 9.63×10−25 | 5.56 | 41 | 141 |
GO:0090257 | regulation of muscle system process | 4.29×10−24 | 5.76 | 41 | 146 |
GO:0030239 | myofibril assembly | 1.6×10−26 | 1.66 | 26 | 42 |
Kidney cortex | |||||
GO:0055085 | transmembrane transport | 2.03×10−18 | 29.19 | 83 | 757 |
GO:0007588 | excretion | 1.83×10−10 | 2.47 | 17 | 64 |
GO:0072006 | nephron development | 6.35×10−09 | 3.43 | 18 | 89 |
GO:0006814 | sodium ion transport | 8.87×10−08 | 4.47 | 19 | 116 |
GO:0072348 | sulfur compound transport | 1.74×10−05 | 0.89 | 7 | 23 |
Liver | |||||
GO:0008202 | steroid metabolic process | 8.68×10−46 | 15.33 | 90 | 267 |
GO:0032787 | monocarboxylic acid metabolic process | 3.34×10−35 | 24.57 | 100 | 428 |
GO:0006805 | xenobiotic metabolic process | 4.1×10−30 | 8.04 | 53 | 140 |
GO:0044282 | small molecule catabolic process | 2×10−28 | 14.7 | 69 | 256 |
GO:1901605 | alpha-amino acid metabolic process | 7.38×10−25 | 11.54 | 57 | 201 |
Lung | |||||
GO:0002684 | positive regulation of immune system process | 2.53×10−37 | 40.21 | 134 | 606 |
GO:0006954 | inflammatory response | 2.23×10−25 | 32.64 | 101 | 492 |
GO:0001816 | cytokine production | 4.95×10−25 | 31.32 | 98 | 472 |
GO:0046649 | lymphocyte activation | 1.2×10−24 | 31.12 | 97 | 469 |
GO:0009607 | response to biotic stimulus | 2.18×10−24 | 39.28 | 111 | 592 |