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Table 1 Fitting the statistical helix model to the relative contact frequencies observed in wild-type (upper part, rows 2–4) and triple KO (lower part, rows 5–7) mouse ES cells (mESCs)

From: Distinct polymer physics principles govern chromatin dynamics in mouse and Drosophila topological domains

 

WT vs H1 TKO mESC

K *10 3

S (kb)

<D > (nm)

<P > (nm)

Sh (kb)

1

mouse liver gene-rich

890 ± 70

2.7 ± 0.1

287 ± 5

160 ± 9

97 ± 1

2

WT mESC gene-rich (Fig. 2a)

1,070 ± 80

2.7 ± 0.1

255 ± 8

201 ± 13

85 ± 2

3

WT mESC gene-poor (Fig. 2b)

1,880 ± 360

3.7 ± 0.3

262 ± 18

213 ± 31

87 ± 5

4

WT mESC gene-desert (Fig. 2c)

1,380 ± 370

3.8 ± 0.3

208 ± 44

264 ± 77

72 ± 13

5

H1TKO gene-rich (Fig. 3a)

1,810 ± 140

3.1 ± 0.1

268 ± 8

230 ± 14

83 ± 2

6

H1TKO gene-poor (Fig. 3b)

2,270 ± 430

3.7 ± 0.3

269 ± 19

224 ± 30

83 ± 5

7

H1TKO gene-desert (Fig. 3c)

2,620 ± 840

3.9 ± 0.4

264 ± 105

380 ± 162

86 ± 28

  1. Parameters obtained for mouse liver cells [4] are indicated for comparisons (row 1). Remarkable values are indicated in bold (see text)