Skip to main content

Table 1 Fitting the statistical helix model to the relative contact frequencies observed in wild-type (upper part, rows 2–4) and triple KO (lower part, rows 5–7) mouse ES cells (mESCs)

From: Distinct polymer physics principles govern chromatin dynamics in mouse and Drosophila topological domains

  WT vs H1 TKO mESC K *10 3 S (kb) <D > (nm) <P > (nm) Sh (kb)
1 mouse liver gene-rich 890 ± 70 2.7 ± 0.1 287 ± 5 160 ± 9 97 ± 1
2 WT mESC gene-rich (Fig. 2a) 1,070 ± 80 2.7 ± 0.1 255 ± 8 201 ± 13 85 ± 2
3 WT mESC gene-poor (Fig. 2b) 1,880 ± 360 3.7 ± 0.3 262 ± 18 213 ± 31 87 ± 5
4 WT mESC gene-desert (Fig. 2c) 1,380 ± 370 3.8 ± 0.3 208 ± 44 264 ± 77 72 ± 13
5 H1TKO gene-rich (Fig. 3a) 1,810 ± 140 3.1 ± 0.1 268 ± 8 230 ± 14 83 ± 2
6 H1TKO gene-poor (Fig. 3b) 2,270 ± 430 3.7 ± 0.3 269 ± 19 224 ± 30 83 ± 5
7 H1TKO gene-desert (Fig. 3c) 2,620 ± 840 3.9 ± 0.4 264 ± 105 380 ± 162 86 ± 28
  1. Parameters obtained for mouse liver cells [4] are indicated for comparisons (row 1). Remarkable values are indicated in bold (see text)