Table 2 Counts of two SNP haplotypes. Counts of two SNP haplotypes with 1–4 alleles for chromosome 21 before and after filtering to remove the loci with more than two 2 SNP haplotypes. Removing any pair of adjacent loci creates a new two SNP haplotype. But the efficacy of the filtering is indicated by the 90 % reduction in loci with > 2 haplotypes after filtering