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Table 2 Malaria outcomes by age group

From: Stool microbiota composition is associated with the prospective risk of Plasmodium falciparum infection

Outcome

Age Group

P value

 

3–5 mo (n = 26)

6 mo–1 y (n = 41)

2–5 y (n = 37)

6–11 y (n = 44)

12–17 y (n = 24)

18–25 y (n = 28)

 

Median days from enrollment to first malaria episodea (95 % CI)

227 (159–249)

NE

134 (109 – 176)

142 (120 – 257)

NE

NE

<0.0001*

Median parasite density for first malaria episodes in parasites/μL (interquartile range)

14,400 (9,600 – 47,850)

38,740 (18,210 – 173,400)

19,800 (8,700 – 57,680)

16,300 (5,700 – 76,300)

13,920 (7,412 – 24,000)

10,720 (9,012 – 14,080)

0.19**

Individuals with ≥1 malaria episodes (% of age group)

4 (15 %)

5 (12 %)

13 (35 %)

13 (30 %)

1 (4.2 %)

0

<0.001***

  1. Abbreviations: CI, confidence interval; NE, not estimated because >50 % of individuals remained free of malaria during the study period
  2. aMalaria defined as ≥2500 parasites/μL, an axillary temperature of ≥37.5 °C within 24 h, and no other cause of fever discernible by physical exam
  3. *log-rank test
  4. **Kruskal-Wallis test
  5. *** Fisher Exact Test
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BMC Genomics

ISSN: 1471-2164

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