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Table 2 Malaria outcomes by age group

From: Stool microbiota composition is associated with the prospective risk of Plasmodium falciparum infection

Outcome Age Group P value
  3–5 mo (n = 26) 6 mo–1 y (n = 41) 2–5 y (n = 37) 6–11 y (n = 44) 12–17 y (n = 24) 18–25 y (n = 28)  
Median days from enrollment to first malaria episodea (95 % CI) 227 (159–249) NE 134 (109 – 176) 142 (120 – 257) NE NE <0.0001*
Median parasite density for first malaria episodes in parasites/μL (interquartile range) 14,400 (9,600 – 47,850) 38,740 (18,210 – 173,400) 19,800 (8,700 – 57,680) 16,300 (5,700 – 76,300) 13,920 (7,412 – 24,000) 10,720 (9,012 – 14,080) 0.19**
Individuals with ≥1 malaria episodes (% of age group) 4 (15 %) 5 (12 %) 13 (35 %) 13 (30 %) 1 (4.2 %) 0 <0.001***
  1. Abbreviations: CI, confidence interval; NE, not estimated because >50 % of individuals remained free of malaria during the study period
  2. aMalaria defined as ≥2500 parasites/μL, an axillary temperature of ≥37.5 °C within 24 h, and no other cause of fever discernible by physical exam
  3. *log-rank test
  4. **Kruskal-Wallis test
  5. *** Fisher Exact Test