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Table 2 Overview table of the analysis of differential gene expression

From: T-REx: Transcriptome analysis webserver for RNA-seq Expression data

Contrast

Total number of genes

Up-regulated

Down-regulated

A_F71Y-WT

4176

72

9

B_R61K-WT

4176

126

15

C_R61H-WT

4176

219

25

Null-WT

4176

282 (196/212)

47 (27/29)

  1. The numbers of up- and down-regulated genes were determined using default cutoffs p-value ≤ 0.05 and fold-change ≥ 2. Within brackets p-value ≤ 0.05 and fold change ≥ 3 as was mentioned in Brinsmade et al. and our pipeline, respectively