Fig. 5
From: C/D box sRNA-guided 2′-O-methylation patterns of archaeal rRNA molecules
A chaperone function for C/D box sRNAs in long distant 16S rRNA folding. In Nanoarchaeum equitans, the guide regions of sR17 and sR15 exhibit extended complementary to the two strands of helix 28 and 30 of 16S rRNA respectively. The sRNA-rRNA interactions (left) position the distant rRNA sequences into close proximity. Release of the sRNAs following methylation at positions A915, G930 G1218 and U1371 is postulated to play a critical role in the efficient folding of helices 28, 29 and 30 in the nascent 16S rRNA (right)