Male and female mice show significant differences in hepatic transcriptomic response to 2,3,7,8-tetrachlorodibenzo-p-dioxin

Table 2 Number of animals available per experimental group

Time (days)	Dose (μg/kg)	Number: Male (TCDD/Control)	Number: Female (TCDD/Control)
6 h^a	500/0	5/4	5/4
1^a	500/0	4/3	5/1
3^a	500/0	4/4	4/1
4	125/0	4/4	4/4
4	250/0	4/4	4/4
4	500/0	4/4	4/4
4	1000/0	4/4	4/4
6^a	500/0	4/3	5/2

The number of animals employed in each set of experimental conditions varied slightly between the current dose response and previous time-course analyses. At each time point, animals were treated with TCDD or vehicle control (indicated by Dose - TCDD/control). Numbers of male or female mice per group are shown as TCDD/control
^aProkopec et al. [42]

ISSN: 1471-2164