Fig. 7

Dynamic differentially expressed (DE) genes were involved in T and B cell development as well as innate and adaptive immune response. Aa, Ab, and Ac were innate immune response including toll-like receptor signaling pathway, NOD-like receptor signaling pathway, phagosome and lysosome pathway. B indicates the process of B and T lymphocytes lymphopoiesis and the regulation genes in each step. C represents adaptive immune response under APEC infection. Genes in blue color were down-regulated while genes in red color were up-regulated. The pink color indicates significantly changed pathways that were not discussed here. The lowercase a, b, c, d indicate different contrasts: a, day 5 susceptible birds vs. day 5 non-challenged birds; b, day 5 susceptible birds vs. day 5 resistant birds; c, day 5 susceptible birds vs. day 1 susceptible birds; d: day 1 susceptible birds vs. day 1 non-challenged birds. LBP, lipopolysaccharide binding protein; LPS, lipopolysaccharide; PGN, peptidoglycan; N, number