Table 1 Mutant strains hypersensitive to Congo red, caspofungin, and zymolyase

YML008C ^a

ERG6

carbohydrate and lipid metabolism

Methyltransferase, converts zymosterol to fecosterol in the ergosterol biosynthetic pathway

YBL058W ^a

SHP1

cell cycle

UBX domain-containing protein, promotes cell cycle progression by positive regulation of Glc7

YAL023C

PMT2

cell wall and morphogenesis

Protein O-mannosyltransferase of the ER membrane

YDR245W

MNN10

cell wall and morphogenesis

Subunit of a Golgi mannosyltransferase complex

YNL084C ^a

END3

cell wall and morphogenesis

EH domain-containing protein involved in endocytosis and cell wall and cytoskeletal organization

YOR035C ^a

SHE4

cell wall and morphogenesis

Protein containing a UCS domain, binds to myosin motor domains to regulate myosin function

YGL173C

KEM1

protein and RNA metabolism

5'-3' exonuclease, component of cytoplasmic processing (P) bodies involved in mRNA decay

YKL054C ^a

DEF1

protein and RNA metabolism

RNAPII degradation factor, enables ubiquitination of RNAPII in an elongation complex

YJL080C ^a

SCP160

protein and RNA metabolism

Essential RNA-binding G protein effector of mating response pathway

YDL006W ^a

PTC1

signaling pathways and response to stress

2C protein phosphatase involved in the dephosphorylation of multiple MAP kinases

YDR264C

AKR1

signaling pathways and response to stress

Palmitoyl transferase, acts as a negative regulator of pheromone response pathway

YDR477W ^a

SNF1

signaling pathways and response to stress

AMP-activated serine/threonine kinase involved in derepression of glucose-repressed genes

YHR030C ^a

SLT2

signaling pathways and response to stress

Serine/threonine MAP kinase of the CWI pathway involved in maintenance of cell wall integrity

YJL095W ^a

BCK1

signaling pathways and response to stress

MAPKKK acting in CWI signaling pathway

YCR020W-B

HTL1

transcription and chromatin remodeling

Component of the RSC chromatin remodeling complex

YBL093C

ROX3

transcription and chromatin remodeling

Subunit of the RNA polymerase II mediator complex

YJL115W

ASF1

transcription and chromatin remodeling

Nucleosome assembly factor involved in chromatin assembly and disassembly

YOL148C ^a

SPT20

transcription and chromatin remodeling

Subunit of the SAGA transcriptional regulatory complex

YEL044W ^a

IES6

transcription and chromatin remodeling

Component of the INO80 chromatin remodeling complex

YJL204C ^a

RCY1

vesicular trafficking and transport

F-box protein involved in recycling endocytosed proteins

YLL043W

FPS1

vesicular trafficking and transport

Aquaglyceroporin, plasma membrane channel, involved in efflux of glycerol and xylitol

YLR138W

NHA1

vesicular trafficking and transport

Na+/H+ antiporter involved in sodium and potassium efflux through the plasma membrane

YOR332W ^a

VMA4

vesicular trafficking and transport

Subunit E of the V1 domain of the vacuolar H + −ATPase (V-ATPase)

YKL080W ^a

VMA5

vesicular trafficking and transport

Subunit C of the V1 peripheral membrane domain of V-ATPase

YGR020C ^a

VMA7

vesicular trafficking and transport

Subunit F of the V1 peripheral membrane domain of V-ATPase

YGR105W

VMA21

vesicular trafficking and transport

Integral membrane protein required for V-ATPase function

YHR060W ^a

VMA22

vesicular trafficking and transport

Protein that is required for vacuolar H + −ATPase (V-ATPase) function

YKL119C ^a

VPH2

vesicular trafficking and transport

Integral membrane protein required for V-ATPase function