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Fig. 4 | BMC Genomics

Fig. 4

From: Malat1 as an evolutionarily conserved lncRNA, plays a positive role in regulating proliferation and maintaining undifferentiated status of early-stage hematopoietic cells

Fig. 4

The analysis of gene expression and cell proliferation. a EML cell were induced with ATRA for indicated time points. The expression of p53, Malat1, Gata2 and EKLF1 were detected using qRT-PCR, β-actin was used as a loading control, and the means ± SD of three independent experiments are shown. Significant changes were detected from the group of 48 h induction (P < 0.05 vs uninduced control). b EML cells were treated with or without (mock) ATRA for indicated time points, the graph showed the rate of growth plotted on a liner scale, the means ± SD of three independent experiments are shown, P < 0.05 vs Mock control

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