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Table 3 Gene ontology and KEGG pathway analysis of gonad differentiation candidates

From: Identification of candidate gonadal sex differentiation genes in the chicken embryo using RNA-seq

Gene ontology category

Gene count

%

P-value

Biological process

   

 Tube development

19

2.7

1.90E-06

 Regulation of cell proliferation

30

4.3

1.40E-06

 Respiratory tube development

12

1.7

2.20E-05

Cellular component

   

 Extracellular region

50

7.2

1.20E-05

 Cell surface

14

2

9.40E-04

 Extracellular region part

28

4

1.60E-03

Molecular Function

   

 Lipid binding

15

2.1

2.70E-03

 Growth factor activity

11

1.6

3.90E-03

 ATPase activity

7

1

4.10E-03

KEGG pathway Term

Gene count

%

P-value

 Focal adhesion

21

3

2.90E-04

 Dorso-ventral axis formation

5

0.7

1.30E-02

 Regulation of actin cytoskeleton

16

2.3

2.20E-02

 ECM-receptor interaction

9

1.3

2.60E-02

 Cytokine-cytokine receptor interaction

13

1.9

5.00E-02

  1. Genes showing DE expression at E6 but not at E4.5 were analysed for gene ontology and KEGG pathway enrichment using DAVID software [48, 49]. The top 3 gene ontology categories for biological process, cellular component and molecular function are shown, along with the gene count, percentage of total genes input and the P-value. The top 5 KEGG pathways are shown for the same data set
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BMC Genomics

ISSN: 1471-2164

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