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Table 2 miRNA targets dys-regulated more than 2-fold in serum of C57BL/6NCrl mice following 4 w low-fat diet after 8 w high-fat diet-induced obesity vs. 12 w high-fat diet-induced obesity (P-value < 0.05)

From: Weight-reduction through a low-fat diet causes differential expression of circulating microRNAs in obese C57BL/6 mice

Up-regulated Down-regulated
DIO + LFD Fold (log2) p-value DIO + LFD Fold (log2) p-value
mmu-miR-16 3.48 0.00 mmu-miR-1983 −3.29 0.05
mmu-let-7i 3.23 0.01 mmu-miR-5112 −2.39 0.02
mmu-miR-26a 2.57 0.02 mmu-miR-1894 −2.18 0.02
mmu-miR-17 2.38 0.02 mmu-miR-5109 −1.88 0.01
mmu-miR-107 2.35 0.02 mmu-miR-711 −1.80 0.00
mmu-miR-451 2.34 0.00 mmu-miR-351* −1.37 0.04
mmu-miR-195 2.28 0.01 mmu-miR-700 −1.19 0.01
mmu-miR-20a 2.06 0.01 mmu-miR-1940 −1.15 0.03
mmu-miR-25 1.88 0.03 mmu-miR-204* −1.14 0.02
mmu-miR-15b 1.85 0.01 mmu-miR-125b −1.09 0.03
mmu-miR-15a 1.83 0.01    
mmu-let-7b 1.73 0.00    
mmu-let-7a 1.69 0.00    
mmu-let-7c 1.64 0.02    
mmu-miR-103 1.61 0.01    
mmu-let-7f 1.57 0.01    
mmu-miR-106a 1.56 0.01    
mmu-miR-106b 1.48 0.04    
mmu-miR-93 1.37 0.01    
mmu-miR-23b 1.34 0.02    
mmu-miR-21 1.23 0.01    
mmu-miR-223 1.18 0.04    
mmu-miR-30b 1.16 0.02    
mmu-miR-221 1.11 0.01    
mmu-miR-19b 1.06 0.02    
mmu-miR-92a 1.05 0.02    
mmu-miR-200c 1.03 0.02    
mmu-miR-873 1.00 0.04