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Table 3 The most enriched KEGG pathways of target genes for 23 differentially expressed miRNAs between the sera of C57BL/6NCrl mice during obesity and weight reduction by low-fat diet

From: Weight-reduction through a low-fat diet causes differential expression of circulating microRNAs in obese C57BL/6 mice

Pathway Count of genes P-value Pathway ID
Metabolic pathways 1024 2.11E06 ko01100
MAPK signaling pathway 514 1.82E05 ko04010
Regulation of actin cytoskeleton 471 3.09E05 ko04810
Biosynthesis of secondary metabolites 392 4.72E05 ko05200
Focal adhesion 342 6.21E10 ko04510
Insulin signaling pathway 318 5.13E05 ko04910
Calcium signaling pathway 295 5.34E05 ko04020
Cytokine-cytokine receptor interaction 228 2.16E04 ko04060
Tight junction 172 4.22E06 ko04530
Phagosome 144 2.14E05 ko04145
Adipocytokine signaling pathway 117 1.27E04 ko04920