Fig. 7
From: Depletion of yeast PDK1 orthologs triggers a stress-like transcriptional response
Transcriptional response of Pkh-depleted cells to heat shock. a Venn diagrams of the number of genes with considered up-regulated (upper panel) and down-regulated (lower panel) mRNA expression under heat sock stress in the wild-type CML476 (WT) and SDP8 strains. b The expression patterns of the wild-type CML476 (WT) and SDP8 cells treated with doxycycline for 24 h and incubated at 40 °C for 40 min were compared with those of the same cells in the absence of the heat stress. A set of 803 genes with data in both strains that are differentially expressed at least in one of the strains were hierarchically clustered (complete linkage clustering, uncentered correlation) using the Gene Cluster software (v. 2.11) and visualized with Java TreeView (v 3.0). The relevant functional categories of genes in some clusters are denoted. c The mRNA levels (in –fold change) determined by DNA microarrays for the PAU family of genes after heat shock are represented for the CML476 (WT, empty circles) and SDP8 (filled circles) strains