Table 2 Stress response-related genes up-regulated by progressive depletion of Pkh

APJ1

X

X

Chaperone of the HSP40 family.

CPR6

X

X

Peptidyl-prolyl cis-trans isomerase (cyclophilin).

CTA1

X

Catalase A.

GAC1

X

Regulatory subunit for Glc7p type-1 protein phosphatase (PP1).

GAD1

X

Glutamate decarboxylase.

GRE1

X

X

Hydrophilin essential in desiccation-rehydration process.

GRE3

X

Aldose reductase involved .

HSP12

X

X

Plasma membrane protein that protects membranes from desiccation.

HSP26

X^a

Small heat shock protein (sHSP) with chaperone activity.

HSP31

X

Methylglyoxalase that converts methylglyoxal to D-lactate.

HSP33

X

Possible chaperone and cysteine protease.

HSP42

X^a

Small heat shock protein (sHSP) with chaperone activity.

HSP78

X

Oligomeric mitochondrial matrix chaperone.

HSP82

X^a

Hsp90 chaperone.

HSP104

X^a

X

Disaggregase.

MCR1

X

Mitochondrial NADH-cytochrome b5 reductase.

MDJ1

X

Co-chaperone that stimulates HSP70 protein Ssc1p ATPase activity.

ORM2

X

Protein that mediates sphingolipid homeostasis.

OXR1

X

Protein of unknown function required for oxidative damage resistance.

PRX1

X

Mitochondrial peroxiredoxin with thioredoxin peroxidase activity.

SNQ2

X

Plasma membrane ATP-binding cassette (ABC) transporter.

SOD2

X

Mitochondrial manganese superoxide dismutase.

SSA3

X

ATPase involved in protein folding and the response to stress.

SSA4

X_a

Heat shock protein that is highly induced upon stress.

SSE2

X^a

X

Member of the heat shock protein 70 (HSP70) family.

TSA2

X

Stress inducible cytoplasmic thioredoxin peroxidase.

UBC5

X^a

Ubiquitin-conjugating enzyme.

UGA2

X

Succinate semialdehyde dehydrogenase.