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Table 3 Transcription factors mainly affected by progressive depletion of Pkh

From: Depletion of yeast PDK1 orthologs triggers a stress-like transcriptional response

 

8 h of doxycycline

24 h of doxycycline

 

Number of

 

Number of

 

T.F.

Target genes

p-value

Target genes

p-value

Msn2

72

1.00E-15

183

0

Msn4

58

1.52E-11

152

0

Spt23

51

2.77E-13

148

0

Rlm1

38

0

94

0

Mga2

37

2.38E-11

103

0

Adr1

37

2.00E-15

86

0

Crz1

28

4.50E-14

68

0

Rgm1

28

0

59

0

Wtm2

19

1.00E-15

31

0

Ric1

18

9.08E-05

64

0

Tog1

17

1.28E-11

35

0

Com2

17

5.04E-13

31

0

Gis1

12

2.58E-04

52

0

Swi4

31

6.18E-08

81

1.00E-15

Hot1

12

2.10E-12

21

1.00E-15

Hsf1

28

1.32E-02

108

3.00E-15

Flo8

26

3.44E-10

56

5.90E-14

Cbf1

40

5.62E-09

97

6.70E-14

Rpi1

15

6.54E-11

28

1.00E-13

Sko1

31

1.78E-09

70

2.49E-13

Pdr1

39

3.78E-09

90

2.78E-12

Cin5

48

2.47E-08

118

3.72E-12

Gat4

6

1.19E-02

29

7.35E-12

Yap6

29

1.12E-07

65

6.90E-10

  1. The set of genes up-regulated by incubation of SDP8 cells with 100 μg/ml doxycycline for 8 or 24 h are ranked by transcription factor, according to the Rank by TF application of the Yeastract platform and using the DNA binding plus expression evidence and TF acting as activator. The number of genes whose expression is controlled by each transcription factor is shown. A score for each transcription factor is given by a p-value that denotes the overrepresentation of the given transcription factor targeted genes in the list of up-regulated genes relative to the regulations of that transcription factor targeted genes in the whole Yeastract database
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BMC Genomics

ISSN: 1471-2164

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