Fig. 8

Orthologs of RxLR-dEER-like proteins within downy mildew pathogen genomes and Phytophthora spp. genomes: High confidence RxLR-dEER-like proteins from the secretome of downy mildew and Phytophthora spp. genomes were predicted and orthology analyses were performed with OrthoMCL to predict orthologs of RxLR-dEER-like proteins. Pha, Hpa, Pca, Pin, Pso, and Prm refer to Pl. halstedii, Hy. arabidopsidis, Ph. capsici, Ph. infestans, Ph. sojae, and Ph. ramorum, respectively. a Venn diagram showing the number of orthologs among the four Phytophthora spp. genomes. b Table summarising the number of orthologs shared by downy mildews and Phytophthora spp. genomes. c Sequence alignments of the three candidate orthologs of putative RxLR-dEER proteins among the six genomes. Multiple sequence alignments were performed using Mafft and alignment graphics were generated using Jalview. Cleavage sites predicted by SignalP are highlighted by red circles, RxLR/dEER-like motifs are highlighted by red boxes